Glyphosate is Not an Endocrine Disruptor: Weight of Evidence vs Key Characteristics for Endocrine Disruption Assessment

D Farmer, CJ Borgert, D Saltmiras, JE Klaunig
Regulatory WoE assessments are clear that GLY does not show EATS modalities. • The methodological deficiencies of KCs explain the incorrect classification of glyphosate’s potential as an ED using this novel approach compared to the application of wellestablished WoE approaches developed by regulatory agencies over the past decade. • ED KCs like other KCs have not been validated against negative controls and the GLY data is an ideal example of a negative control and demonstrates how the KC approach lacks a means to get to a negative conclusion about a chemical’s ED properties.