by Michael Boyd | Jul 25, 2023 | Publications
The 2008 National Research Council report “Phthalates and Cumulative Risk Assessment: Tasks Ahead,” rejected the underlying premises of TEQ-like approaches – e.g., chemicals are true congeners; are metabolized and detoxified similarly; produce the same biological...
by Michael Boyd | Jul 25, 2023 | Publications
One molecule, caffeine, was further tested in rat pubertal assays at the tumorigenic doselevel and at dose-levels relevant for human consumption. In females pubertal parameters (vaginal opening, estrus cycle), ovarian weight and Fsh and prolactin transcript levels...
by Michael Boyd | Jul 25, 2023 | Publications
The appeal also notes that most national and international statutes delineating the discretion of regulators are ambiguous about what rules of evidence ought to apply. Those statutes should be revised to ensure that the evidence for regulatory action is grounded on...
by Susan Borgert | Jul 25, 2023 | Publications
Endocrine-disrupting substances (EDS) may have certain biological effects including delayed effects, multigenerational effects, and may display nonmonotonic dose–response (NMDR) relationships that require careful consideration when determining environmental hazards....
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