Principles for Identifying Endocrine-Active and Endocrine-Disrupting Chemicals

An endocrine disruptor is a natural or man made substance, external to the body, that evidence shows directly alters the function of the endocrine system, and consequently causes negative health impacts that are confirmed through scientific study.

Through the efforts of governments, academia and industry, considerable progress has been made to develop methods, tests and data that could help answer questions about endocrine active and endocrine disrupting chemicals. As the science is refined and improved, certain principles should be incorporated into testing programs to ensure that results are reliable and relevant to regulators and the public.