Are Key Characteristics Valid for Identifying Endrocrine Hazards?

CJ Borgert
- The KCs for EDCs were developed based on KCs for carcinogens. - Flaws in the KC approach for carcinogens have not been addressed or corrected and were repeated in the KCs for EDCs. - The KC approach requires less data and fewer resources than the WoE approach but lacks the basic elements of rigor and reproducibility that should be a standard requirement for regulatory science.